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German Study: Evolving Corona Virus Similar to HIV

Quarantine and a safe distance between people are aimed at preventing the corona virus from infiltrating human bodies through the respiratory system. But when the virus actually infiltrates the body, in which part of it does it hide?

The emerging coronavirus can hide in the throat, and every time a person coughs, it spreads the virus in the air and causes infections for those around it.

In order to stay healthy and contain SARS-Cove-2, health experts are advised to stay at home and stay away from others.

But efforts to combat corona over a broad population may not be very clear. The small virus that causes Covid-19 is smart, elusive, and powerful that can challenge ordinary vaccines.

Those findings are the findings of a new study by a team of 18 scientists in Germany and published in the Nature journal this month.

In two separate laboratories, scientists carefully studied the prevalence of SARS-Cove-2 in the bodies of nine patients, and recorded daily measurements in order to understand each stage of infection.

The scientists wrote that "an active recurrence of the virus in the upper respiratory tract puts chances of containing Covid-19 in its proper perspective."

Observers of ongoing studies on the new virus praised the work done by the German team, according to the American Daily Beast website which quoted professor of pathology, immunology and laboratory medicine at the University of Florida Medical School, David Ostrov, as saying that there was "huge news" in the journal Nature.

Among other things, German scientists have revealed that the multiplication of the SARS-Cove-2 virus begins in the throat and not in the lungs. For this reason, a simple throat scan is sufficient to detect infection with the virus, and there is likely no need for a disturbing nose scan.

The virus is mostly spread by people who cough on each other. Depending on the site, you are less likely to develop an emerging corona by touching the same touchpad or toilet handle than an infected person has touched.

He says it is safe for a person with Covid-19 to leave hospital 10 days after symptoms appear.

But the German study also has bad news, as the antibodies our bodies produce in response to Covid-19 do not really destroy the virus. This makes the new corona similar to HIV.

That conclusion has implications for international efforts to develop vaccines and other treatments.

In addition to the important information for doctors, scientists and the general public, the German study tells a story that helps to understand the global epidemic.

Peter Kulczynski, a virologist and biotechnology investor, summarized what was reported in the Nature journal on Twitter. He wrote that "the study reveals a distinct trick that SARS-Cove-2 has learned that makes it worse than the first SARS virus," which killed about 800 people in 2003.

Viruses enter the cells of our bodies by interacting with specific proteins. Once in, the viruses hijack the cell mechanisms in order to reproduce themselves.

When that happens, our bodies sometimes panic, and they trigger a strong immune response that can reach very far that may lead to our illness or even death.

SARS-Cove-2 prefers ACE2 protein. "Think of the protein as a specific door handle that defines the virus how it wants it to open," Kulcinski explains.

There are a lot of ACE2 proteins in our throats, which are an excellent place for the virus to hide, reproduce and prepare to spread.

From the throat, the virus can spread internally to the lungs, making it more dangerous for the host body. With each cough, the virus is directed outward.

Ostrov, a professor at the University of Florida, focused on what German scientists have found about the antibodies that our bodies produce through a process called seroconversion.

According to the study, "When cycles of viral burden are aligned, it appears that there is no abrupt elimination of the virus during a serum reactivity coup." Instead, "serum reactivity reversal early in the second week coincides with a slow and steady decline in viral load in sputum."

This means that antibodies are not effective in removing the virus, according to Ostrov, who added, "This is important when considering viruses and vaccines. HIV also stimulates the production of antibodies that fail to eliminate the virus, like many viruses such as hepatitis C virus."

"People have tried and failed to develop vaccines against such viruses, so we should not be sure that the vaccine strategy will succeed." But this does not mean stopping attempts, as vaccines may eventually work.

If not, scientists may consider changing their strategy. Instead of relying on vaccines, doctors may treat newborns as well as AIDS patients, that is, through a combination of drugs that manage and not eliminate infection.

Source / agencies